Holding(s) in Company

TR-1: Notifications of Major Interests in Shares

1: Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Abcam Plc

2: Reason for notification (yes/no)

An acquisition or disposal of voting rights

x

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

3. Full name of person(s) subject to the notification

obligation:

 T Rowe Price Associates, Inc

4. Full name of shareholder(s) (if different from 3.):

 JP Morgan Chase

Bank of New York Mellon Bank, NA

State Street Bank & Trust Co

5. Date of the transaction (and date on which the threshold

is crossed or reached):

20 September 2013

6. Date on which issuer notified:

24 September 2013

7. Threshold(s) that is/are crossed or reached:

5%

8: Notified Details

A: Voting rights attached to shares

Class/type of share If possible use ISIN code

GB00B6774699

Situation previous to the triggering transaction

Number of shares

Number of voting rights

9,818,952

9,818,952

Resulting situation after the triggering transaction

Number of shares

Number of voting rights

Percentage ofvoting rights

Direct

Indirect

Direct

Indirect

10,583,060

0

10,583,060

0.000%

5.30%

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ conversion period/date

No. of voting rights that may be acquired(if the instrument exercised/converted)

Percentage of voting rights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Exerciseprice

Expirationdate

Exercise/Conversionperiod

Number of votingrights instrumentrefers to

% of voting rights

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

 10,583,060

5.30%

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable:

 T. Rowe Price Associates, Inc (TRPA)serves as investment advisor, with dispositive and voting authority, to various institutional clients that own shares in Abcam plc, including T. Rowe Price New Horizons Fund, which owns 5,691,066 shares. Such shares are registered in the following names:

JP Morgan Chase - 2,754,393

Bank of New York Mellon Bank , N.A. - 157,603

State Street Bank & Trust Co - 7,671,064

Proxy Voting:

10. Name of the proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14. Contact name:

Jeff Iliffe, Chief Financial Officer

15. Contact telephone number:

01223 696000