Holding(s) in Company

TR-1: Notifications of Major Interests in Shares

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Advanced Oncotherapy plc

2. Reason for notification (yes/no)

An acquisition or disposal of voting rights

x

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify):__________

3. Full name of person(s) subject to notification obligation:

Gabriel Urwitz

4. Full name of shareholder(s) (if different from 3):

AB Segulah

5. Date of transaction (and date on which the threshold is crossed or reached if different):

2013-04-26

6. Date on which issuer notified:

2013-04-29

7. Threshold(s) that is/are crossed or reached:

Above 10%

8: Notified Details

A: Voting rights attached to shares

Class/type of shares

If possible use ISIN code

ORDINARY

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Number of shares

35,100,000

Number of voting rights

35,100,000

Number of shares

38,100,000

Number of voting rights

Percentage of voting rights

Direct

0

Indirect

Direct

0

Indirect

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ conversion period/date

No. of voting rights that may be acquired (if the instrument exercised/converted)

Percentage of voting rights

Total (A+B)

Number of voting rights

Percentage of voting rights

38,100,000

10.6%

9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14 Contact name:

Gabriel Urwitz

15. Contact telephone name:

0046 8 402 87 00