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Holding(s) in Company

16th May 2012 10:35

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi

1. Identity of the issuer or the underlying SOURCE BIOSCIENCE PLC issuer of existing shares to which voting

rights are attached: ii

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights X An acquisition or disposal of qualifying financial instruments which

may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights Other (please specify): 3. Full name of person(s) subject to Killik & Co LLP the notification obligation: iii

4. Full name of shareholder(s) (if TDWCS LLP (on behalf of various different from 3.):iv

discretionary clients of Killik & Co LLP) 5. Date of the transaction and date 14/5/12 on which the threshold is crossed or reached: v 6. Date on which issuer notified: 15/5/12 7. Threshold(s) that is/are crossed Crossed above 5% or reached: vi, vii 8. Notified details:A: Voting rights attached to shares viii, ixClass/type of Situation previous Resulting situation after shares to the triggering the triggering transaction transaction if possible Number Number % of voting using Number of Number of rights x the ISIN CODE of Voting of voting Shares Rights shares rights Direct Direct xi Indirect Direct Indirect xii ORD GBP0.02 8,586,131 8,586,131 10,586,131 10,586,131 5.2% GB0009739649 B: Qualifying Financial Instruments Resulting situation after the triggering transaction

Type of financial Expiration Exercise/ Number of voting % of voting

instrument date xiii Conversion Period rights that may be rights xiv acquired if the instrument is exercised/ converted.

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments xv, xvi

Resulting situation after the triggering transaction Type of Exercise Expiration Exercise/ Number of voting % of voting financial price date xvii Conversion rights instrument rights xix, xx instrument period refers to xviii Nominal Delta Total (A+B+C) Number of voting rights Percentage of voting rights 10,586,131 5.2%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: xxi

Proxy Voting: 10. Name of the proxy holder: 11. Number of voting rights proxy holder will cease to hold: 12. Date on which proxy holder will cease to hold voting rights: 13. Additional information: 14. Contact name: Julie Steele 15. Contact telephone number: 020 7337 0400

XLON

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