6th Dec 2007 11:00
AstraZeneca PLC06 December 2007 TR-1: NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Identity of the issuer or the underlying issuer of existing shares to whichvoting rights are attached: AstraZeneca PLC 2. Reason for the notification (place an X inside the appropriate bracket/s) An acquisition or disposal of voting rights: ( X ) An acquisition or disposal of financial instruments which may result in theacquisition of shares already issued to which voting rights are attached: ( ) An event changing the breakdown of voting rights: ( ) Other (please specify) : ( ) 3. Full name of person(s) subject to the notification obligation: Capital Group International, Inc. 4. Full name of shareholder(s) (if different from 3.) : ................. 5. Date of the transaction (and date on which the threshold is crossed orreached if different): 3 December 2007 6. Date on which issuer notified: 5 December 2007 7. Threshold(s) that is/are crossed or reached: 3% 8. Notified details: ................. A: Voting rights attached to shares Class/type of shares if possible Situation previous to the Triggering transactionusing the ISIN CODE Number of shares Number of voting Rights Ordinary Shares 44,074,040 44,074,040 Resulting situation after the triggering transaction Class/type of shares if Number of shares Number of voting rights % of voting rightspossible using the ISIN CODE Direct Indirect Direct Indirect Direct Indirect Ordinary Shares 43,596,228 43,596,228 2.9873% B: Financial Instruments Resulting situation after the triggering transaction Type of Expiration Date Exercise/Conversion Number of voting rights % of voting rightsfinancial Period/ Date that may be acquired if theinstrument instrument is exercised/ converted. N/A Total (A+B) Number of voting rights % of voting rights 43,596,228 2.9873% 9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable: ................. Proxy Voting: 10. Name of the proxy holder: ................. 11. Number of voting rights proxy holder will cease to hold: ................. 12. Date on which proxy holder will cease to hold voting rights: ................. 13. Additional information: Commencing 20 January 2007, The Capital Group Companies, Inc., no longer reportsownership of securities. Capital Group International, Inc. and Capital Researchand Management Company now report relevant holdings separately for the purposesof the new DTR Handbook. 14. Contact name: Justin Hoskins - Assistant Secretary 15. Contact telephone number: 020 7304 5112 This information is provided by RNS The company news service from the London Stock ExchangeRelated Shares:
Astrazeneca