Holding(s) in Company

Ambrian plc

("Ambrian" or the "Company")

Holding(s) in Company

The Company announces that it received notification on 24 November 2016 that AMG Invest GmbH now holds an interest in 9,225,700 ordinary shares of 1p each ("Ordinary Shares"), representing approximately 3.65 per cent. of the existing issued share capital of the Company carrying voting rights.

For further information, please contact:-

Ambrian plc

Roger Clegg, COO +44 (0)20 7634 4700

Cenkos Securities plc

Neil McDonald +44 (0)131 220 9771

Nick Tulloch +44 (0)131 220 9772