Holding(s) in Company

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARES

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Synairgen plc

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

Yes 

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

Admittance of new shares to the market

 Yes

3. Full name of person(s) subject to the notification obligation:

F&C Asset Management plc

4. Full name of shareholder(s) (if different from 3.):

See box 9 below

5. Date of the transaction and date on which the threshold is crossed or reached:

Placing 16/06/2009

6. Date on which issuer notified:

16/07/2009

7. Threshold(s) that is/are crossed or reached:

5, 10, 11, 12%

8. Notified details:

A: Voting rights attached to shares

Class/type of shares

if possible using the ISIN CODE

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Number of Shares

Number of Voting Rights

Number of shares

Number of voting rights

% of voting rights

Direct

Direct

Indirect

Direct

Indirect

GB00B0381Z20 GBP 0.01

646,471

646,471

7,618,600

-

7,618,600

-

12.75%

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/  Conversion  Period

Number of voting rights that may be acquired if the instrument is exercised/ converted.

% of voting rights

 -

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Exercise  price

Expiration  date

Exercise/ Conversion  period

Number of voting  rights instrument  refers to

% of voting rights

 -

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

7,618,600

12.75%

9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of proxy holder:

F&C Asset Management plc

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14 Contact name:

Mike Bassi, F&C Asset Management plc

15. Contact telephone name:

0131 718 1093

Annex: Notification of major interests in shares

A: Identity of the persons or legal entity subject to the notification obligation

Full name 

(including legal form of legal entities)

Synairgen plc

Contact address 

(registered office for legal entities)

Mailpoint 810, Level F  South Block Southampton General Hospital Tremona Road Southampton SO16 6YD

Phone number & email

Tel: +44 (0) 23 8051 2800 Fax: +44 (0)23 8051 2800

[email protected] (FD)

Other useful information 

(at least legal representative for legal persons)

B: Identity of the notifier, if applicable

Full name

Mike Bassi, F&C Asset Management plc

Contact address

80 George Street, Edinburgh EH2 3BU

Phone number & email

0131 718 1093

[email protected]

Other useful information

(e.g. functional relationship with the person or legal entity subject to the notification obligation)

C: Additional information