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Holding(s) in Company

15th May 2012 16:38

TR-1: NOTIFICATION OF MAJOR INTEREST IN SHARESi

1. Identity of the issuer or the underlying SOURCE BIOSCIENCE PLC issuer of existing shares to which voting

rights are attached: ii

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights X An acquisition or disposal of qualifying financial instruments which

may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights Other (please specify): 3. Full name of person(s) subject to MR S VARKEY the notification obligation: iii 4. Full name of shareholder(s) (if different from 3.):iv 5. Date of the transaction and date 14 MAY 2012 on which the threshold is crossed or reached: v 6. Date on which issuer notified: 14 MAY 2012 7. Threshold(s) that is/are crossed HOLDING BELOW 3% or reached: vi, vii 8. Notified details:A: Voting rights attached to shares viii, ixClass/type of Situation previous Resulting situation after shares to the triggering the triggering transaction transaction if possible Number Number % of voting using Number of Number of rights x the ISIN CODE of Voting of voting Shares Rights shares rights Direct Direct xi Indirect Direct Indirect xii ORD GBP0.02 17,635,457 17,635,457 3,522,581 3,522,581 1.73% GB0009739649 B: Qualifying Financial Instruments Resulting situation after the triggering transaction

Type of financial Expiration Exercise/ Number of voting % of voting

instrument date xiii Conversion Period rights that may be rights xiv acquired if the instrument is exercised/ converted.

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments xv, xvi

Resulting situation after the triggering transaction Type of Exercise Expiration Exercise/ Number of voting % of voting financial price date xvii Conversion rights instrument rights xix, xx instrument period refers to xviii Nominal Delta Total (A+B+C) Number of voting rights Percentage of voting rights 3,522,581 1.73%

9. Chain of controlled undertakings through which the voting rights and/or the financial instruments are effectively held, if applicable: xxi

Proxy Voting: 10. Name of the proxy holder: 11. Number of voting rights proxy holder will cease to hold: 12. Date on which proxy holder will cease to hold voting rights: 13. Additional information: 14. Contact name: COMPANY SECRETARY, SOURCE BIOSCIENCE PLC 15. Contact telephone number: 0115 9739012

XLON

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