Holding(s) in Company

For filings with the FSA include the annex

For filings with issuer exclude the annex 

TR-1: Notifications of Major Interests in Shares

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

Physiomics plc

2. Reason for notification (yes/no)

An acquisition or disposal of voting rights

YES

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached 

NO

An event changing the breakdown of voting rights

NO

Other (please specify):______________

NO

3. Full name of person(s) subject to notification obligation:

Barclays PLC

4. Full name of shareholder(s) (if different from 3):

Barclays Stockbrokers Ltd

Gerrard Investment Management Ltd

5. Date of transaction (and date on which the threshold is crossed or reached if different):

18 March 2009

6. Date on which issuer notified:

19 March 2009

7. Threshold(s) that is/are crossed or reached:

7% to 8%

8: Notified Details

A: Voting rights attached to shares

Class/type of shares

If possible use ISIN code

GB00B04QT956

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Number of shares

49,410,727

Number of voting rights

49,410,727

Number of shares

51,410,727

Number of voting rights

Percentage of voting rights

Direct

0

Indirect

51,410,727

Direct

Indirect

8.23%

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ conversion period/date 

No. of voting rights that may be acquired (if the instrument exercised/converted)

Percentage of voting rights

N/A

N/A

N/A

N/A

N/A

Total (A+B)

Number of voting rights

Percentage of voting rights

51,410,727

8.23%

9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable:

Barclays Capital Stockbrokers Ltd

Gerrard Investment Management Ltd

Proxy Voting:

10. Name of proxy holder:

N/A

11. Number of voting rights proxy holder will cease to hold:

N/A

12. Date on which proxy holder will cease to hold voting rights:

N/A

13. Additional information:

14 Contact name:

Geoff Smith

15. Contact telephone name:

020 7116 2913