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Holding(s) in Company

24th Jan 2006 11:02

Alizyme PLC24 January 2006 SCHEDULE 10 NOTIFICATION OF MAJOR INTERESTS IN SHARES 1. Name of listed company Alizyme plc 2. Name of shareholder with a major interest Prudential plc and certain of its subsidiary companies 3. Please state whether notification indicates that it is regarding the holdingof the shareholder named in 2 above; in respect of a non-beneficial interest; orin the case of an individual holder if it is a holding of that person's spouseor children under the age of 18 Shareholders named in 2 above 4. Name of the registered holder(s) and, if more than one holder, the number ofshares held by each of them Registered Holder Holding %BANK OF NEW YORK (NOMS) LTD/636922 152,612 0.09NORTRUST NOMINEE LTD A/C MHF01 26,031 0.01NORTRUST NOMINEE LTD A/C MKK01 11,802,621 6.60NORTRUST NOMS LTD A/C MEB01 2,986,237 1.67NORTRUST NOMS LTD A/C MEL01 176,515 0.10PRUCLT HSBC GIS NOM (UK) PAC AC 2,555,036 1.43PRUCLT HSBC GIS NOM (UK) PPL AC 2,201,848 1.23 Total Notifiable Interest 19,900,900 11.13 5. Number of shares / amount of stock acquired1,371,173 ordinary shares 6. Percentage of issued class0.77% 7. Number of shares / amount of stock disposedNot applicable 8. Percentage of issued classNot applicable 9. Class of securityOrdinary shares of 2p each 10. Date of transactionNot disclosed 11. Date listed company informed23 January 2006 12. Total holding following this notification19,900,900 13. Total percentage holding of issued class following this notification11.13% 14. Any additional informationNot applicable 15. Name of contact and telephone number for queries David CampbellTel. No. +44 (0)1223 896000 16. Name and signature of duly authorised officer of the listed companyresponsible for making this notification David Campbell, Company Secretary Date of notification 24 January 2006 The FSA does not give any express or implied warranty as to the accuracy of thisdocument or material and does not accept any liability for error or omission.The FSA is not liable for any damages (including, without limitation, damagesfor loss of business or loss of profits) arising in contract, tort or otherwisefrom the use of or inability to use this document, or any material contained init, or from any action or decision taken as a result of using this document orany such material. This information is provided by RNS The company news service from the London Stock Exchange

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