Holding(s) in Company

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached: ii

Verona Pharma plc

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

√

An acquisition or disposal of qualifying financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An acquisition or disposal of instruments with similar economic effect to qualifying financial instruments

An event changing the breakdown of voting rights

Other (please specify):

3. Full name of person(s) subject to the notification obligation: iii

Vivo Ventures VI, LLC

4. Full name of shareholder(s)

(if different from 3.):iv

Vivo Ventures fund VI, LP

Vivo Ventures VI Affiliates Fund, LP

5. Date of the transaction and date on which the threshold is crossed or

reached: v

July 29, 2016

6. Date on which issuer notified:

July 29, 2016

7. Threshold(s) that is/are crossed or reached: vi, vii

1.62% to 2.46% Change at Combined Interest Level

  8. Notified details:

A: Voting rights attached to shares viii, ix

Class/type of shares

if possible using the ISIN CODE

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Number of

Shares

Number of

Voting Rights

Number of shares

Number of voting rights

% of voting rights x

Direct

Direct xi

Indirect xii

Direct

Indirect

GB00B06GSH43

16,400,000

16,400,000

63,098,468

63,098,468

2.46%

B: Qualifying Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date xiii

Exercise/ Conversion Period xiv

Number of voting rights that may be

acquired if the instrument is

exercised/ converted.

% of voting rights

C: Financial Instruments with similar economic effect to Qualifying Financial Instruments

xv, xvi

Resulting situation after the triggering transaction

Type of financial instrument

Exercise price

Expiration date xvii

Exercise/ Conversion

period xviii

Number of voting rights instrument refers to

% of voting rights xix,

xx

Nominal

Delta

Total (A+B+C)

Number of voting rights

Percentage of voting rights

63,098,468

2.46%

  Proxy Voting:

10. Name of the proxy holder:

See Section 4

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14. Contact name:

Vivo Capital, LLC Attn: Cinthia Sheu

15. Contact telephone number:

+1-650-688-0818

A: Identity of the persons or legal entity subject to the notification obligation

Full name

(including legal form of legal entities)

Vivo Ventures VI, LLC

Contact address

(registered office for legal entities)

575 High Street, suite 201, Palo Alto, CA 94301

Phone number & email

650-688-0818; acha@vivocapital.net

Other useful information

(at least legal representative for legal persons)

Albert Cha, Managing Member

B: Identity of the notifier, if applicable

Full name

Albert Cha

Contact address

575 High Street, suite 201, Palo Alto, CA 94301

Phone number & email

650-688-0818; acha@vivocapital.net

Other useful information

(e.g. functional relationship with the person or legal entity subject to the notification obligation)

Albert Cha, Managing Member