Holding(s) in Company

TR-1: Notifications of Major Interests in Shares

1. Identity of the issuer or the underlying issuer of existing shares to which voting rights are attached:

SMITHS GROUP PLC

2. Reason for notification (yes/no)

An acquisition or disposal of voting rights

Yes

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached 

An event changing the breakdown of voting rights

Other (please specify):______________

3. Full name of person(s) subject to notification obligation:

CAPITAL GROUP INTERNATIONAL, INC.

4. Full name of shareholder(s) (if different from 3):

5. Date of transaction (and date on which the threshold is crossed or reached if different):

15 DECEMBER 2008

6. Date on which issuer notified:

16 DECEMBER 2008

7. Threshold(s) that is/are crossed or reached:

4%

8: Notified Details

A: Voting rights attached to shares

Class/type of shares

If possible use ISIN code

Situation previous to the triggering transaction

Resulting situation after the triggering transaction

Number of shares

Number of voting rights

Number of shares

Direct

Number of voting rights

Percentage of voting rights

Direct

Indirect

Direct

Indirect

ORD 37.5p - GB00B1WY2338

15,487,335

15,487,335

16,204,104

4.1656%

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financial instrument

Expiration date

Exercise/ conversion period/date 

No. of voting rights that may be acquired (if the instrument exercised/converted)

Percentage of voting rights

n/a

Total (A+B)

Number of voting rights

Percentage of voting rights

16,204,104

4.1656%

9. Chain of controlled undertakings through which the voting rights and /or the financial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of proxy holder:

11. Number of voting rights proxy holder will cease to hold:

12. Date on which proxy holder will cease to hold voting rights:

13. Additional information:

14 Contact name:

15. Contact telephone name:

Number of shares

Percent of Outstanding

Capital Group International, Inc. ("CGII") holdings

16,204,104

4.166%

Holdings by CGII Management Companies and Funds:

- Capital Guardian Trust Company

12,979,174

3.337%

- Capital International Limited

1,736,430

0.446%

- Capital International S.A.

224,500

0.058%

- Capital International, Inc.

1,264,000

0.325%