Grant for BtB US Trials

30 April 2012

Ultrasis plc

("Ultrasis" or the "Company")

University of Pittsburgh Medical School Secures

Research Funding for Major Beating the BluesUS Trial

Ultrasis, the leading provider of cognitive behavioural therapy for stress and mild to moderate depression delivered by computer, is pleased to announce a substantial research grant for its US-specific version of "Beating the Blues" ("BtB US").

Dr Bruce L. Rollman, MD MPH, Professor of Medicine, Psychiatry, and Clinical and Translational Science at the University of Pittsburgh Medical School has been awarded a US$2.6 million grant by the National Institute of Mental Health of America ("NIMH") to undertake a four year study of BtB US.

The research will evaluate the effectiveness of BtB US in primary care and Dr Rollman believes the study findings are likely to impact the way certain mental health conditions are managed in primary care in the USA.

Nigel Brabbins, Chief Executive of Ultrasis, said:

"We congratulate Dr Rollman on securing this important and significant grant from NIMH. I see this as a major step forward in our strategic plan to broaden the use of Beating the Blues across the USA, underlining the importance of Beating the Blues as a cost effective solution in addressing mental health conditions.

Although Ultrasis will not benefit financially from this grant, I am confident that it will raise substantially the awareness of Beating the Blues and U², our joint venture with UPMC. Continuous research is important in maintaining Beating the Blues as the leading evidence-based computer delivered cognitive behavioural therapy program for stress and depression."

For further details, please visit:

www.ultrasis.com/downloads/U2%20Interactive%20Research%20Funding%20Press%20Release.pdf, www.U2interactive.com and www.beatingthebluesus.com.

-ENDS-

For further information contact:

Chris Lawrance