Form 8 (DD) - Shire plc

FORM 8 (DD) PUBLIC DEALING DISCLOSURE BY A PARTY TO AN OFFER OR PERSON ACTING IN CONCERT (INCLUDING DEALINGS FOR THE ACCOUNT OF DISCRETIONARY INVESTMENT CLIENTS) Rules 8.1, 8.2 and 8.4 of the Takeover Code (the "Code") 1. KEY INFORMATION (a) Identity of the party to the offer or David Stoutperson acting in concert making the disclosure: (b) Owner or controller of interests and shortpositions disclosed, if different from 1(a): The naming of nominee or vehicle companies isinsufficient (c) Name of offeror/offeree in relation to Shire plcwhose relevant securities this form relates: Use a separate form for each offeror/offeree (d) Status of person making the disclosure: Director of Offeree e.g. offeror, offeree, person acting in concertwith the offeror/offeree (specify name ofofferor/offeree) (e) Date dealing undertaken: 30 September 2014 (f) Has the party previously disclosed, or is NOit today disclosing, under the Code in respectof any other party to this offer? 2. POSITIONS OF THE PERSON MAKING THE DISCLOSURE (a) Interests and short positions in the relevant securities of the offeror orofferee to which the disclosure relates following the dealing Class of relevant security: 1 ADS = 3 x 5p ordinary shares Interests Short positions Number % Number % (1) Relevant securities owned 435 ADS = 1,305

The Code can be viewed on the Panel's website at www.thetakeoverpanel.org.uk .