Director's interests in the shares of BTG plc

17 June 2010

Directors' Interests in the shares of BTG plc

The following shares in the Company have been released to Dr Louise Makin.

1. An award of 285,975 shares was made under the Company's performance share plan on 15 June 2007. Following testing of the performance conditions, 284,734 shares vested and were released to Louise Makin on 15 June 2010. Following vesting, 145,945 were sold at a price of 188.4538p to satisfy the resulting liability for tax and national insurance and she retained the balance of 138,789 shares.

2. On 15 June 2007, half of Louise Makin's annual bonus earned in relation to the year ended 31 March 2007 was awarded in shares under the Company's deferred share bonus plan. This amounted to 98,991 shares. The shares were due for release to her on 15 June 2010 as long as she remained in employment with the Company.

On 1 April 2010 the Remuneration Committee approved the early vesting of this award and its conversion into a cash award, at a price of 178.30p per share, on that date. The value, net of deductions for tax and national insurance, was deposited with the Company's Guernsey Trust, to be held on her behalf until 15 June 2010.

Following release of the funds on 15 June 2010, the full amount was used to buy 55,149 shares in the Company at a cost of 186.9525p per share, which Louise Makin has retained The total value, including dealing costs, was £104,134.

Following these transactions, Louise Makin's shareholding has increased from 178,883 to 372,821 shares, being 0.145% of the issued share capital.

- ends -

Contact for Queries: Andy Burrows

Director of Investor Relations

Telephone: 020 7575 1741