Director/PDMR Shareholding

1.

Details of PDMR / person closely associated with them ("PCA")

a)

Name

Mr Richard Howell

2.

Reason for the notification

a)

Position / status

Non-Executive Director

b)

Initial notification / amendment

Initial Notification

3.

Details of the issuer, emission allowance market participant, auction platform, auctioneer or auction monitor

a)

Name

Life Science REIT Plc

b)

LEI

213800RG7JNX7K8F7525

4.

Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date; and (iv) each place where transactions have been conducted

a)

Description of the financial instrument

Identification Code

Ordinary Shares of 1 pence each

ISIN: GB00BP5X4Q29

b)

Nature of the transaction

Purchase of Ordinary Shares

c)

Price(s) and volume(s)

d)

Aggregated information

-Aggregated volume

-Price

30,000

£22,258.50

e)

Date of the transaction

6 December 2022

f)

Place of the transaction

London Stock Exchange (XLON)