Director/PDMR Shareholding

Sinclair IS Pharma plc ("Sinclair IS" or the "Company")

Director dealings

15 December 2011, Sinclair IS Pharma plc (AIM:SPH.L) ("Sinclair IS"), the international specialty pharma company, was informed today that Stuart Swanson, Non-Executive Director, has recently acquired ordinary shares of 1p each ("Ordinary Shares") in the Company as follows:

9 December 2011 318,000 Ordinary shares at 23.23p

12 December 2011 72,000 Ordinary shares at 23.5p

13 December 2011 243,538 Ordinary shares at 23.5p

14 December 2011 146,283 Ordinary Shares at 23.46p

Following these purchases, Mr Swanson is interested in 2,087,107 Ordinary Shares, 0.52% of the issued share capital of the Company.

For further information please contact:

Sinclair IS Pharma plc Tel: +44 (0) 20 7467 6920

Chris Spooner

Alan Olby

Jefferies International Limited (NOMAD and Broker) Tel: +44 (0) 20 7029 8000

Julian Smith

Thomas Rider

Financial Dynamics Tel: +44 (0) 20 7831 3113

Ben Atwell

Stephanie Cuthbert