Director/PDMR Shareholding

1

Details of Person Discharging Managerial Responsibility("PCMR")/person closely associated with them ("PCA")

(a)

Name

Dr Ian Rutter

2

Reason for the notification

(b)

Position/status

Non-executive director

(c)

Initial notification/ amendment

Initial notification

2

Details of the transaction(s): section to be repeated for (i) each type of instrument; (ii) each type of transaction; (iii) each date: and (iv) each place where transactions have been conducted

(a)

Description of the financial instrument

Ordinary shares of 12.5p each

Legal Entity Identifier

213800Y5CJHXOATK7X11

(b)

Nature of the transaction

Share purchase

(c)

Price(s) and volume(s)

Price(s)

Volume(s)

£1.088

7,500

(d)

Aggregated information

Aggregated volume price

Single transaction

£8,156.25

(e)

Date of transaction

22 March 2017

(f)

Place of transaction

London Stock Exchange (xlon)