Director/PDMR Shareholding

GlaxoSmithKline plc

 Notification of Transactions of Directors, Persons Discharging Managerial Responsibilities or Connected Persons

In accordance with DTR 3.1.4 R(1)(c) I give details of changes in the interests of Dr P J T Vallance, a Person Discharging Managerial Responsibilities, in the ordinary shares of GlaxoSmithKline plc ('GSK'). GSK was advised on 4 May 2016 that Dr P J T Vallance's Connected Person, Dr S Dexter, acquired 844 GSK ordinary shares, at a price of 1510.58 pence per share, following the re-investment of the dividend paid to shareholders on 14 April 2016.

V A Whyte

Company Secretary

4 May 2016