Director/PDMR Shareholding

Notification of Transactions of Directors, Persons Discharging Managerial Responsibility or Connected Persons

The Administrators of the SmithKline Beecham Mid-Term Incentive Plan notified the Company and the under-mentioned person on 18 April 2012 of an increase in his interests in American Depositary Shares (ADSs) at a price of $45.47 per ADS following the re-investment of the dividend paid to shareholders on 12 April 2012.

This notification relates to transactions notified in accordance with Disclosure and Transparency Rule 3.1.4R(1)(a).

V A Whyte

Company Secretary

18 April 2012