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Director/PDMR Shareholding

8th Jan 2008 16:00

AstraZeneca PLC08 January 2008 Transaction by Person Discharging Managerial Responsibilities Disclosure Rules DTR 3.1.2R We hereby inform you that on 31 December 2007, Dr John Patterson, a Director ofAstraZeneca PLC and a person discharging managerial responsibilities, gave anirrevocable instruction to exercise options over 625 AstraZeneca PLC USD0.25Ordinary Shares as follows: - option over 374 shares at an option price of 1756 pence per share grantedunder the AstraZeneca Savings Related Share Option Scheme - option over 251 shares at an option price of 2262 pence per share grantedunder the AstraZeneca Savings Related Share Option Plan. We further inform you that the exercise date of these options was 4 January2008. Following these exercises Dr Patterson holds options over 236,091 AstraZenecaPLC UDS0.25 Ordinary Shares. We confirm that Dr Patterson retained the 625 shares acquired and, as a result,his interest in shares has increased to 131,912 AstraZeneca PLC UDS0.25 OrdinaryShares, which represents approximately 0.009% of the current issued capital. G H R Musker Company Secretary 8 January 2008 This information is provided by RNS The company news service from the London Stock Exchange

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Astrazeneca
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