Director/PDMR Shareholding

GW Pharmaceuticals PLC

("GW Pharmaceuticals" or the "Company")

NOTIFICATION OF INTERESTS OF DIRECTORS AND CONNECTED PERSONS

Porton Down, UK, 14 September 2010: GW Pharmaceuticals (AIM: GWP) hereby provides notification that the company has today been notified of the following series of share transactions entered into by Dr Geoffrey Guy, a Director and Executive Chairman, and Justin Gover, Managing Director, of the Company.

Mr Gover today exercised options over 471,250 ordinary shares of 0.1 pence each. These options were 10 year options which would have expired if not exercised before 2nd October 2010. Mr Gover subsequently sold 105,000 ordinary shares at a price of 100 pence per share, sufficient to cover just the cost arising from exercising the aforementioned options. Following these transactions, Mr Gover's beneficial ownership of GW Pharmaceuticals plc ordinary shares has increased to 3,983,668 shares, representing 3.0% of the Company's current issued share capital.

Dr Guy today exercised options over 139,333 ordinary shares of 0.1 pence each. These options were 10 year options which would have expired if not exercised before 15 January 2011. Dr Guy subsequently sold 100,000 ordinary shares at a price of 100 pence per share, sufficient to cover the cost and tax liabilities arising from exercising the aforementioned options. Following these transactions, Dr Guy's beneficial ownership of GW Pharmaceuticals plc ordinary shares has increased to 18,364,448 shares, representing 14.0% of the Company's current issued share capital.

The total number of shares outstanding in the Company is 131,197,792 ordinary shares of 0.1 pence each.

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