Director/PDMR Shareholding

 GlaxoSmithKline plc

Notification of Transactions of Directors, Persons Discharging Managerial Responsibilities or Connected Persons

In accordance with DTR 3.1.4 R (1) (a), I give below details of a change in the interests of Ms Emma Walmsley, a Person Discharging Managerial Responsibilities, in the ordinary shares of GlaxoSmithKline plc (the "Company").

Following the vesting on 1 May 2016 of 25% of an award made on 1 May 2010 under the GlaxoSmithKline Deferred Investment Award Plan, Ms Walmsley will receive a cash payment of 1470.75 pence per ordinary share in respect of 14,784.871 notional ordinary shares.

The Company and Ms Walmsley were advised of this transaction on 4 May 2016.

V A Whyte

Company Secretary

4 May 2016