Director/PDMR Shareholding

Notification of Transactions of Directors, Persons Discharging Managerial Responsibility or Connected Persons

The Administrators of the GlaxoSmithKline Annual Investment Plan notified the Company and the under mentioned person on 14 October 2010 of an increase in their interests in Ordinary shares, purchased at a price of £13.15 per share on 13 October 2010, following the re-investment of the dividend paid to shareholders on 7 October 2010 -

This notification relates to transactions notified in accordance with Disclosure and Transparency Rule 3.1.4R(1)(a).

S M Bicknell

Company Secretary

14 October 2010