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Director Shareholding

15th Mar 2005 12:00

AstraZeneca PLC15 March 2005 Dealing by DirectorsCompanies Act 1985 Sections 324/329 We hereby inform you that on 14 March 2005, Sir Tom McKillop, a Director of theCompany, exercised an option over 24,513 AstraZeneca PLC USD0.25 Ordinary Sharesat an option price of 891 pence per share. The option was granted to Sir TomMcKillop in March 1995 under the Company's 1994 Executive Share Option Schemeand is due to expire on 26 March 2005 if not exercised before then. As a result of this exercise, Sir Tom McKillop holds options over 547,351Ordinary Shares of AstraZeneca PLC. We also inform you that on 14 March 2005, Sir Tom McKillop sold 10,180 of theshares acquired from the exercise at an average price of 2176 pence per share inorder to meet the cost of exercising the option. Following these transactions, Sir Tom McKillop has increased his holding in theCompany by 14,333 shares to 92,168 shares, which represents approximately 0.006%of the issued ordinary capital of the Company. G H R MuskerCompany Secretary15 March 2005 This information is provided by RNS The company news service from the London Stock Exchange

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Astrazeneca
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