Director Shareholding Amendment

Destiny Pharma plc

("Destiny Pharma" or the "Company")

Director Shareholding Amendment

Brighton, United Kingdom - 18 November 2022 - Destiny Pharma (AIM: DEST), a clinical stage biotechnology company focused on the development of novel medicines to prevent life threatening infections, announces that due to an administrative oversight at the time of Nigel Brooksby's appointment to the Board, as announced on 26 May 2022, his shareholding in Destiny Pharma was not made known to the Company. The Company can now clarify that Mr. Brooksby holds a beneficial interest in 348,750 ordinary shares in Destiny Pharma representing 0.48 per cent. of the Company's issued share capital.

For further information, please contact:

Destiny Pharma plc

Neil Clark, CEO

Shaun Claydon, CFO

+44 (0) 127 370 4440

[email protected]

Optimum Strategic Communications

Mary Clark / Manel Mateus / Eleanor Cooper

+44 (0) 203 922 0891

[email protected] 

finnCap Ltd (Nominated Adviser and Joint Broker)

Geoff Nash / Abigail Kelly / George Dollemore, Corporate Finance

Alice Lane / Nigel Birks / Harriet Ward, ECM

+44 (0) 207 220 0500

MC Services AG

Anne Hennecke / Andreas Burckhardt

+49-211-529252-12

Stern IR - US

Janhavi Mohite

+1-212-362-1200

[email protected]

About Destiny Pharma

Destiny Pharma is a clinical stage, innovative biotechnology company focused on the development of novel medicines that can prevent life-threatening infections. Its pipeline has novel microbiome-based biotherapeutics and XF drug clinical assets including NTCD-M3, a Phase 3 ready treatment for the prevention of C. difficile infection (CDI) recurrence which is the leading cause of hospital acquired infection in the US and also XF-73 nasal gel, which has recently completed a positive Phase 2b clinical trial targeting the prevention of post-surgical staphylococcal hospital infections including MRSA. It is also co-developing SporCov, a novel, biotherapeutic product for the prevention of COVID-19 and other viral respiratory infections and has earlier grant funded XF research projects.

For further information on the company, please visit https://www.destinypharma.com.