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Director Declaration

15th Nov 2012 16:30

Director Declaration

November 15, 2012 - Shire plc announces that, in accordance with Listing Rule LR 9.6.14, its non-executive director, Anne Minto, has been appointed as a Non-Executive Director to the Board of Directors of Tate & Lyle PLC, with effect from December 1, 2012.

Tony GuthrieDeputy Company Secretary

For further information please contact:

Investor Relations Eric Rojas [email protected] +1 781 482 0999 Sarah Elton-Farr [email protected] +44 1256 894157 Notes to editors

Shire enables people with life-altering conditions to lead better lives.

Through our deep understanding of patients' needs, we develop and provide healthcare in the areas of:

* Behavioral Health and Gastro Intestinal conditions * Rare Diseases * Regenerative Medicine

as well as other symptomatic conditions treated by specialist physicians.

We aspire to imagine and lead the future of healthcare, creating value for patients, physicians, policymakers, payors and our shareholders.

Registered in Jersey, No. 99854, 22 Grenville Street, St Helier, Jersey JE4 8PXPress Release

www.shire.com

XLON

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