26th Nov 2007 15:00
BLOCK LISTING SIX MONTHLY RETURN Basingstoke, UK and Philadelphia, US - November 26, 2007 - Shire plc Name of applicant: SHIRE PLC Name of scheme: STOCK PURCHASE PLAN Period of return: From: 26 May 2007 To: 25 November 2007
Balance under scheme from previous 1,604,351 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted Nil under scheme during period: Balance under scheme not yet issued/ 1,604,351 allotted at end of period Number and class of securities 2,000,000 on 25 November 2005 originally listed and the date of admission Total number of securities in issue at 555,598,449
the end of the period Name of applicant: SHIRE PLC Name of scheme: 1996 EXECUTIVE SHARE OPTION SCHEME Period of return: From: 26 May 2007 To: 25 November 2007
Balance under scheme from previous 538,673 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 1,475 under scheme during period: Balance under scheme not yet issued/ 537,198 allotted at end of period Number and class of securities 1,200,000 on 25 November 2005 originally listed and the date of admission Total number of securities in issue at 555,598,449
the end of the period Name of applicant: SHIRE PLC Name of scheme: 2000 EXECUTIVE SHARE OPTION SCHEME Period of return: From: 26 May 2007 To: 25 November 2007
Balance under scheme from previous 3,297,892 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 1,186,134 under scheme during period: Balance under scheme not yet issued/ 2,111,758 allotted at end of period
Number and class of securities 10,000,000 on 25 November 2005 originally listed and the date of
admission Total number of securities in issue at 555,598,449
the end of the period Name of applicant: SHIRE PLC Name of scheme: SHIRE PLC SHARESAVE SCHEME Period of return: From: 26 May 2007 To: 25 November 2007
Balance under scheme from previous 886,041 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 2,577 under scheme during period: Balance under scheme not yet issued/ 883,464 allotted at end of period Number and class of securities 1,000,000 on 25 November 2005 originally listed and the date of admission Total number of securities in issue at 555,598,449
the end of the period Name of applicant: SHIRE PLC Name of scheme: BIOCHEM PHARMA STOCK OPTION PLAN Period of return: From: 26 May 2007 To: 25 November 2007
Balance under scheme from previous 88,291 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted Nil under scheme during period: Balance under scheme not yet issued/ 88,291 allotted at end of period Number and class of securities 3,600,000 on 25 November 2005 originally listed and the date of admission Total number of securities in issue at 555,598,449
the end of the period Name of applicant: SHIRE PLC Name of scheme: EXCHANGEABLE SHARES IN SHIRE ACQUISITION INC Period of return: From: 26 May 2007 To: 25 November 2007
Balance under scheme from previous 1,145,088 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 897,561 under scheme during period: Balance under scheme not yet issued/ 247,527 allotted at end of period Number and class of securities 3,000,000 on 2 February 2006 originally listed and the date of admission Total number of securities in issue at 555,598,449
the end of the period Name of contact: Philip Griffin-Smith - Interim Deputy Company Secretary Address of contact: Shire plc, Lime Tree Way, Hampshire International Business Park, Chinham, Basingstoke, RG24 8EP
Telephone number of contact: +44 1256 894 276
T May
Company Secretary
For further information please contact:
Investor Relations Clĩa Rosenfeld (Rest of the World) +44 1256 894 160 Eric Rojas (North America) +1 484 595 8252 Notes to editorsSHIRE PLC
Shire's strategic goal is to become the leading specialty biopharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on attention deficit and hyperactivity disorder (ADHD), human genetic therapies (HGT), gastrointestinal (GI) and renal diseases. The structure is sufficiently flexible to allow Shire to target new therapeutic areas to the extent opportunities arise through acquisitions. Shire's in-licensing, merger and acquisition efforts are focused on products in niche markets with strong intellectual property protection either in the US or Europe. Shire believes that a carefully selected portfolio of products with strategically aligned and relatively small-scale sales forces will deliver strong results.
For further information on Shire, please visit the Company's website: www.shire.com.
Hampshire International Business Park Chineham Basingstoke Hampshire RG24 8EP United Kingdom Tel +44 (0)1256 894000 Fax +44 (0)1256 894708 www.shire.com Press Release
Registered in England 05492592 Registered Office as above
SHIRE PLCRelated Shares:
Shire