27th Nov 2006 14:40
BLOCK LISTING SIX MONTHLY RETURN Basingstoke, UK and Philadelphia, US - November 27, 2006 - Shire plc Name of applicant: SHIRE PLC Name of scheme: STOCK PURCHASE PLAN Period of return: From: 26 May 2006 To: 25 November 2006
Balance under scheme from previous 1,776,379 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 171,725 under scheme during period: Balance under scheme not yet issued/ 1,604,654 allotted at end of period Number and class of securities 2,000,000 on 25 November 2005 originally listed and the date of admission Total number of securities in issue at 503,484,082
the end of the period Name of applicant: SHIRE PLC Name of scheme: 1996 EXECUTIVE SHARE OPTION SCHEME Period of return: From: 26 May 2006 To: 25 November 2006
Balance under scheme from previous 1,001,174 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 72,509 under scheme during period: Balance under scheme not yet issued/ 928,665 allotted at end of period Number and class of securities 1,200,000 on 25 November 2005 originally listed and the date of admission Total number of securities in issue at 503,484,082
the end of the period Name of applicant: SHIRE PLC Name of scheme: 2000 EXECUTIVE SHARE OPTION SCHEME Period of return: From: 26 May 2006 To: 25 November 2006
Balance under scheme from previous 7,883,924 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 2,870,239 under scheme during period: Balance under scheme not yet issued/ 5,013,685 allotted at end of period
Number and class of securities 10,000,000 on 25 November 2005 originally listed and the date of
admission Total number of securities in issue at 503,484,082
the end of the period Name of applicant: SHIRE PLC Name of scheme: SHIRE PLC SHARESAVE SCHEME Period of return: From: 26 May 2006 To: 25 November 2006
Balance under scheme from previous 952,338 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 292 under scheme during period: Balance under scheme not yet issued/ 952,046 allotted at end of period Number and class of securities 1,000,000 on 25 November 2005 originally listed and the date of admission Total number of securities in issue at 503,484,082
the end of the period Name of applicant: SHIRE PLC Name of scheme: BIOCHEM PHARMA STOCK OPTION PLAN Period of return: From: 26 May 2006 To: 25 November 2006
Balance under scheme from previous 3,589,070 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 48,360 under scheme during period: Balance under scheme not yet issued/ 3,540,710 allotted at end of period Number and class of securities 3,600,000 on 25 November 2005 originally listed and the date of admission Total number of securities in issue at 503,484,082
the end of the period Name of applicant: SHIRE PLC Name of scheme: EXCHANGEABLE SHARES IN SHIRE ACQUISITION INC Period of return: From: 26 May 2006 To: 25 November 2006
Balance under scheme from previous 2,804,100 return: The amount by which the block scheme Nil has been increased, if the scheme has been increased since the date of the last return: Number of securities issued/allotted 1,487,112 under scheme during period: Balance under scheme not yet issued/ 1,316,988 allotted at end of period Number and class of securities 3,000,000 on 2 February 2006 originally listed and the date of admission Total number of securities in issue at 503,484,082
the end of the period Name of contact: Vivienne Hemming - Deputy Company Secretary Address of contact: Shire plc, Lime Tree Way, Hampshire International Business Park, Chinham, Basingstoke, RG24 8EP
Telephone number of contact: +44 1256 894 276
For further information please contact:
Investor Relations Clĩa Rosenfeld (Rest of the World) +44 1256 894 160 Brian Piper (North America) +1 484 595 8252 Notes to editorsSHIRE PLC
Shire's strategic goal is to become the leading specialty pharmaceutical company that focuses on meeting the needs of the specialist physician. Shire focuses its business on central nervous system, gastrointestinal, general products and human genetic therapies. The structure is sufficiently flexible to allow Shire to target new therapeutic areas to the extent opportunities arise through acquisitions. Shire believes that a carefully selected portfolio of products with a strategically aligned and relatively small-scale sales force will deliver strong results.
Shire's focused strategy is to develop and market products for specialty physicians. Shire's in-licensing, merger and acquisition efforts are focused on products in niche markets with strong intellectual property protection either in the US or Europe.
For further information on Shire, please visit the Company's website: www.shire.com.
Hampshire International Business Park Chineham Basingstoke Hampshire RG24 8EP United Kingdom Tel +44 (0)1256 894000 Fax +44 (0)1256 894708 www.shire.com Press Release
Registered in England05492592Registered Office as above
SHIRE PLCRelated Shares:
Shire