Block Listing Six Monthly Return

For Immediate Release

27 November 2009

Name of applicant:

OXFORD BIOMEDICA PLC

Name of scheme:

Share Option Scheme

Period of return:

From:

29 May 2009

To:

27 November 2009

Balance of unallotted securities under scheme(s) from previous return:

4,223,564 Ordinary Shares of 1p each

Plus: The amount by which the block scheme(s) has been increased since the date of the last return (if any increase has been applied for):

None

Less: Number of securities issued/allotted under scheme(s) during period (see LR3.5.7G):

187,025 Ordinary Shares of 1p each

Equals: Balance under scheme(s) not yet issued/allotted at end of period:

4,036,539 Ordinary Shares of 1p each

Name of contact:

Andrew Wood, Company Secretary

Telephone number of contact:

01865 783000