Block Listing Application

BLOCK LISTING APPLICATION

A block listing application has been made for 15,000,000 Ordinary Shares of $0.25 each in AstraZeneca PLC (the "Company") to be admitted to the Official List of the UK Listing Authority and admitted to trading on the London Stock Exchange.

Admission is expected to become effective on 25 August 2011.

The shares will be issued fully paid and will rank pari passu in all respects with the existing ordinary shares of the Company and will be issued pursuant to certain of the Company's employee share plans.

A C N Kemp

Company Secretary

24 August 2011