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Block Listing Application

5th Mar 2013 12:00

SHIRE PLC - Block Listing Application

SHIRE PLC - Block Listing Application

PR Newswire

London, March 5

Block Listing Application

March 5, 2013 - Shire plc (the "Company") (LSE: SHP, NASDAQ: SHPG) herebynotifies the market that application has been made to the UK Listing Authorityand the London Stock Exchange for a total of 90,000 ordinary shares of 5p each("Shares") to be admitted to the Official List. These Shares are being reservedunder a block listing and will be issued pursuant to the Shire Employee StockPurchase Plan.

These Shares will rank pari passu in all respects with the existing issuedShares of the Company.

For further information please contact:

Investor Eric Rojas (erojas@shire.com) +1 781 482 0999Relations Sarah Elton-Farr (seltonfarr@shire.com) +44 1256 894157 Notes to editors

Shire enables people with life-altering conditions to lead better lives.

Through our deep understanding of patients' needs, we develop and providehealthcare in the areas of:

* Behavioral Health and Gastro Intestinal conditions * Rare Diseases * Regenerative Medicine

as well as other symptomatic conditions treated by specialist physicians.

We aspire to imagine and lead the future of healthcare, creating value forpatients, physicians, policymakers, payors and our shareholders.

Registered in Jersey, No. 99854, 22 Grenville Street, St Helier, Jersey JE4 8PX Press Release

www.shire.com


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Shire
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