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Barclays and their holdings in Shire

30th Sep 2005 06:00

30 September 2005Shire Pharmaceuticals Group plc (the "Company")The Company announces that it was notified on 29 September 2005 under Sections198 to 202 of the Companies Act that Barclays PLC, through its associatedcompanies, held a notifiable interest, in aggregate, of 19,812,971 ordinaryshares of ‚£0.05p each in the capital of the Company. These holdings represent4.01 per cent of the issued ordinary share capital of the Company.T MayCompany SecretaryFor further information please contact:Investor Relations Clƒ©a Rosenfeld (Rest of the World) +44 1256 894 160 Brian Piper (North America) +1 484 595 8252 Notes to editorsShire Pharmaceuticals Group plcShire Pharmaceuticals Group plc (Shire) is a global specialty pharmaceuticalcompany with a strategic focus on meeting the needs of the specialist physicianand currently focuses on developing and marketing products in the areas ofcentral nervous system (CNS), gastrointestinal (GI), renal diseases and humangenetic therapies. Shire has operations in the world's key pharmaceuticalmarkets (US, Canada, UK, France, Italy, Spain and Germany) as well as aspecialist drug delivery unit in the US.For further information on Shire, please visit the Company's website: www.shire.com.Hampshire International Business Park Chineham Basingstoke Hampshire RG24 8EP United Kingdom Tel +44 (0)1256 894000 Fax +44 (0)1256 894708 www.shire.com Registered in England 2883758 Registered Office as aboveENDShire Pharmaceuticals Group PLC

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BarclaysShire
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