Appointment of Independent Non-Executive Director

hVIVO plc

("hVIVO", the "Company" or the "Group")

Directorate Change

Appointment of Independent Non-Executive Director

hVIVO plc (AIM: HVO), a full-service Contract Research Organisation (CRO) and the world leader in human challenge clinical trials, announces that further to its announcement on 12 May 2025, the Company has appointed Tracey James as Independent Non-Executive Director from 1 June 2025. Tracey will be Chair of the Audit Committee, and a member of the Remuneration and Nominations Committees.

Tracey is a Chartered Accountant with 26 years' experience working at Grant Thornton UK LLP (Grant Thornton), including 14 years as an Audit Partner. Tracey was a member of Grant Thornton's Oversight Board and also served on the Audit & Risk and Pensions Committees. She has held roles as Director of Finance at Karl Storz Endoscopy Canada, as Senior Independent Director, and Chair of Audit at CT Automotive Group plc and as Vice Chair and Chair of Audit & Risk and a member of the Remuneration Committee at Activate Learning Group. Tracey was also Non-Executive Director and member of the Audit Committee at Places for People Group.

Currently Tracey is a Non-Executive Director at ECO Animal Health Group plc and Gattaca plc. She is also Chair of the Audit & Risk Committee and a member of the Remuneration Committee for both companies.

Yamin 'Mo' Khan, Chief Executive Officer of hVIVO plc, said: "We ae delighted to welcome Tracey to the Board of hVIVO. Tracey brings with her a wealth of experience, especially with AIM listed companies, that will further strengthen the Board. I look forward to working with Tracey and leaning on her expertise as we continue to integrate our diverse portfolio of revenue streams and deliver further progress for our clients and shareholders."

Tracey James

Independent Non-Executive Director

Additional Information on the Board Appointment

The following additional information is provided with regards to the appointment of Tracey Dawn James (née Clements), aged 62, in accordance with Rule 17 and Schedule 2(g) of the AIM Rules for Companies:

Tracey does not hold any shares or options in the Company.

There are no further disclosures required under Rule 17 and Schedule 2(g) of the AIM Rules for Companies.

For further information please contact:

Notes to Editors

hVIVO plc (Ticker: HVO) is full-service Contract Research Organisation (CRO) and the global leader in human challenge trials. The company delivers end-to-end clinical development services to a diverse and expanding client base, including seven of the world's ten largest biopharma companies.

hVIVO specialises in conducting human challenge trials across multiple infectious and respiratory indications, leveraging its state-of-the-art quarantine facility in London-the largest of its kind worldwide. The company also offers comprehensive virology and immunology laboratory services under the hLAB brand.

Through its German subsidiary, CRS, hVIVO operates a 120-bed capacity across Mannheim and Kiel, providing early-phase clinical trial services, including first-in-human and proof-of-concept studies. Its second subsidiary, Venn Life Sciences, offers Early Drug Development Consulting and Biometry services to the biopharma sector.

The Group provides fully integrated drug development solutions from preclinical stages through Phase II trials, alongside patient recruitment via FluCamp. Additionally, its five clinical sites support outpatient Phase II and III trials, ensuring a seamless and efficient pathway from discovery to late-stage development.