Annual Report and Accounts

6 May 2010

Plethora Solutions Holdings plc

Annual Report and Accounts and AGM Notice

Plethora Solutions Holdings plc (AIM: PLE, 'Plethora', 'The Company'), the UK-based speciality pharmaceutical company, announces that that its annual report and accounts for the year ended 31 December 2009 is being posted to shareholders this week along with the Notice of the Annual General Meeting (AGM).

The AGM will be held at 0900h on 27 May 2010 at the offices of Morrison & Foerster, CityPoint, One Ropemaker Street, London, EC2Y 9AW.

The annual report and accounts will be available for download from the Company's website, www.plethorasolutions.co.uk. A printed copy may also be requested by writing to the Company Secretary, Plethora Solutions, 4th Floor, 233 High Holborn, London, WC1V 7DN.

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Enquiries:

About Plethora:

Plethora is focused on the development and marketing of products for the treatment of urological disorders. The Urology Company is Plethora's marketing and distribution business, established in August 2009, to target the UK urology market. The Urology Company markets a range of proprietary, branded and generic pharmaceutical products, together with selected medical devices and nutritional supplements. Products are marketed directly to specialist prescribing physicians, retail pharmacies and directly to consumers.

In addition, Plethora has a portfolio of products at varying stages of development for the treatment of overactive bladder (PSD506), stress urinary incontinence (PSD503), interstitial cystitis (PSD597), gynaecological pain (PSD508), erectile dysfunction (PSD510 - 'Invicorp') and premature ejaculation (PSD502). Plethora is headquartered in the UK and is listed on the London Stock Exchange (AIM: PLE.L).

Further information is available at:

www.plethorasolutions.co.uk and www.theurologyco.com