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Annual Information Update

25th May 2012 07:00

25 May 2012 Source BioScience plc (`Source BioScience', or `the Company') Annual Information Update

For the purposes of complying with its obligations under Prospectus Rule 5.2.1, Source BioScience announces that the information below has been published or made publicly available over the previous 12 months in accordance with laws and rules dealing with regulation of securities, issues of securities and securities markets.

All Company regulatory announcements can be found on the website of the London Stock Exchange www.londonstockexchange.com or the Source BioScience website www.sourcebioscience.com.

1. Announcements made via the Regulatory News Service (`RNS' and `RNS Reach')

The announcements listed below were published by the Company via RNS on the dates indicated:

27/05/2011 Annual Information Update 09/06/2011 Award of Technology Strategy Board Grant (RNS Reach) 09/06/2011 AGM Statement 09/06/2011 Result of AGM 20/06/2011 Launch of Overnight Sequencing Service (RNS Reach) 22/06/2011 Launch of World's Largest Clone & Antibody Resource (RNS Reach) 13/07/2011 NHS Approval for Automated Cervical Cancer Screening 25/07/2011 Notification of Major Interest in Shares 26/07/2011 Half Year Pre-close Trading Update 26/07/2011 Dublin Sequencing Tender 23/08/2011 Half-yearly Report 04/10/2011 Launch of Overnight Sequencing Service in Berlin (RNS Reach) 31/10/2011 Launch of Overnight Sequencing Service in Oxford (RNS Reach) 15/11/2011 Interim Management Statement 19/12/2011 NHS Publishes Guidelines for Automated Cancer Screening 28/12/2011 Purchase of Premises at 1 Orchard Place 12/01/2012 Director/PDMR Shareholding 16/01/2012 Director/PDMR Shareholding 01/02/2012 Adoption of Automated Imaging by Pennine Acute NHS Trust (RNS Reach) 27/02/2012 Change of Advisor 09/03/2012 Notice of Results 20/03/2012 Final Results 02/04/2012 Holding(s) in Company 04/05/2012 Holding(s) in Company 08/05/2012 Holding(s) in Company 08/05/2012 Holding(s) in Company 08/05/2012 Holding(s) in Company 10/05/2012 Launch of Japanese Version of GenomeCubeĀ® (RNS Reach) 15/05/2012 Holding(s) in Company 16/05/2012 Interim Management Statement 16/05/2012 Holding(s) in Company 16/05/2012 Holding(s) in Company 18/05/2012 Notice of AGM

2. Documents filed at Companies House

The Company has submitted the following documents at Companies House on the dates indicated:

28/06/2011 Annual Report and Accounts 2010 06/07/2011 Annual Return 11/01/2012 Change of SAIL address

3. Documents sent to shareholders

The Company has dispatched the following documents to holders of its securities during the last 12 months on the dates indicated:

23/08/2011 Half Year Report 2011 17/05/2012 Annual Report and Accounts 2011 including Notice of AGM

A copy of this Annual Information Update (which also appears on the Company website www.sourcebioscience.com) and all the documents referred to in it, can be obtained from the Company's registered office, Source BioScience plc, 1 Orchard Place, Nottingham Business Park, Nottingham, NG8 6PX.

This annual information update is required by and is being made pursuant to Article 10 of the Prospectus Directive as implemented in the United Kingdom (Prospectus Rule 5.2) and not for any other purpose and neither the Company, nor any other person, takes any responsibility for, or makes any representation, express or implied, as to the accuracy or completeness of, the information which it contains. This information is not necessarily up to date as at the date of this annual information update and the Company does not undertake any obligation to update any such information in the future. Furthermore, such information may have been prepared in accordance with the laws or regulations of a particular jurisdiction and may not comply with or meet the relevant standards of disclosure in any other jurisdiction. This annual information update does not constitute an offer of any securities addressed to any person and should not be relied upon by any person.

For further information, please contact:

Source BioScience plcDr Nick AshCompany Secretary+ 44 (0)115 973 9010www.sourcebioscience.com

XLON

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