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Annual Information Update

19th May 2009 11:24

19 May 2009 Source BioScience plc (`Source BioScience', `the Company' or `the Group') Annual Information Update

For the purposes of complying with its obligations under Prospectus Rule 5.2.1, Source BioScience announces that the information below has been published or made available to the public over the previous 12 months in accordance with laws and rules dealing with regulation of securities, issues of securities and securities markets.

Details of all regulatory announcements for the Company can be found on the London Stock Exchange website at www.londonstockexchange.com or on the Source BioScience website www.sourcebioscience.com.

1. Announcements made via the Regulatory Information Service ("RNS")

The announcements listed below were published by the Company via RNS on thedates indicated. 20/05/2008 Annual Information Update 05/06/2008 Result of AGM 05/06/2008 AGM Statement 27/06/2008 Directorate Change 21/07/2008 Change of Advisor 14/08/2008 Notice of Results 27/08/2008 Capital Reorganisation 27/08/2008 Half-yearly Report 29/08/2008 Director/PDMR Shareholding 29/08/2008 Director/PDMR Shareholding 29/08/2008 Director/PDMR Shareholding 29/08/2008 Director/PDMR Shareholding 19/09/2008 Result of General Meeting 04/11/2008 Expansion of Distributor Network in East Asia 14/11/2008 London DNA Sequencing Facility 19/11/2008 Interim Management Statement 22/12/2008 Capital Reorganisation 10/03/2009 Notice of Results 17/03/2009 Final Results 24/04/2009 Holding(s) in Company 24/04/2009 Change of Advisor 08/05/2009 Notice of AGM 18/05/2009 Interim Management Statement

2. Documents filed at Companies House

The Company has submitted the following documents at Companies House on thedates indicated. 06/07/2008 Annual Return 09/07/2008 Notice of change of directors or secretaries or in their particulars 05/08/2008 Notice of change of directors or secretaries or in their particulars 23/09/2008 Authority to purchase a number of shares 28/10/2008 Auditor's letter of resignation 19/12/2008 Order of Court re capital reorganisation (Section 138) 08/01/2009 Register of members

3. Documents sent to shareholders

The Company has dispatched the following documents to holders of its securities during the last 12 months on the dates indicated.

27/08/2008 Circular relating to the proposed capital reorganisation 27/08/2008 Half yearly report 08/05/2009 Annual Report and Accounts, including Notice of AGM

A copy of this Annual Information Update (which also appears on the Company website www.sourcebioscience.com) and all the documents referred to in it, can be obtained from the Company's registered office, Source BioScience plc, 1 Orchard Place, Nottingham Business Park, Nottingham, NG8 6PX.

This annual information update is required by and is being made pursuant to Article 10 of the Prospectus Directive as implemented in the United Kingdom (Prospectus Rule 5.2) and not for any other purpose and neither the Company, nor any other person, takes any responsibility for, or makes any representation, express or implied, as to the accuracy or completeness of, the information which it contains. This information is not necessarily up to date as at the date of this annual information update and the Company does not undertake any obligation to update any such information in the future. Furthermore, such information may have been prepared in accordance with the laws or regulations of a particular jurisdiction and may not comply with or meet the relevant standards of disclosure in any other jurisdiction. This annual information update does not constitute an offer of any securities addressed to any person and should not be relied upon by any person.

For further information, please contact:

Source BioScience plc

Dr Nick Ash

Managing Director 0115 973 9010

www.sourcebioscience.com

Bishopsgate Communications Ltd

Nick Rome /Gemma O'Hara 0207 562 3350

www.bishopsgatecommunications.com

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