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Annual Information Update

28th Mar 2006 16:00

AstraZeneca PLC28 March 2006 ASTRAZENECA PLC ANNUAL INFORMATION UPDATE As required under the Prospectus (Directive 2003/71/EC) Regulations 2005and paragraph 5.2 of the Prospectus Rules, and following publication of theAnnual Report and Form 20-F Information on 28 February 2006, AstraZenecaPLC is presenting its first Annual Information Update in relation to informationthat has been published or made available to the public between 1 February2005 and 27 March 2006. This Annual Information Update is also being made available on the Investorssection of our website, www.astrazeneca.com. The information referred to in this Annual Information Update was correct at thetime it was published but may now be out of date. 1. Announcements made via a RIS The documents listed below were published via a Regulatory Information Serviceon or around the dates indicated. Date Description of Contents of Announcement 27/03/06 Transaction in Own Shares24/03/06 Transaction in Own Shares20/03/06 Notice of AGM20/03/06 Transaction in Own Shares17/03/06 Transaction in Own Shares14/03/06 Seminar on Merck Arrangements13/03/06 Crestor09/03/06 Patent Writ06/03/06 Director/PDMR Shareholding01/03/06 Director/PDMR Shareholding28/02/06 Director/PDMR Shareholding28/02/06 Director/PDMR Shareholding28/02/06 Annual Report and Accounts23/02/06 Transaction in Own Shares22/02/06 Transaction in Own Shares17/02/06 Transaction in Own Shares16/02/06 Toprol-XL14/02/06 Exanta13/02/06 Transaction in Own Shares10/02/06 Transaction in Own Shares09/02/06 Transaction in Own Shares06/02/06 Transaction in Own Shares03/02/06 Transaction in Own Shares02/02/06 Final Results (in 3 parts)01/02/06 Notice of Results24/01/06 Director/PDMR Shareholding18/01/06 Toprol-XL03/01/06 Seroquel28/12/05 Collaboration Agreement23/12/05 KuDOS Pharmaceuticals22/12/05 Collaboration20/12/05 Holding(s) in Company16/12/05 Transaction in Own Shares15/12/05 Director/PDMR Shareholding15/12/05 Transaction in Own Shares14/12/05 Transaction in Own Shares09/12/05 Transaction in Own Shares08/12/05 Licensing Agreement08/12/05 Transaction in Own Shares07/12/05 Transaction in Own Shares02/12/05 Director/PDMR Shareholding02/12/05 Transaction in Own Shares01/12/05 Transaction in Own Shares30/11/05 Holding(s) in Company29/11/05 Transaction in Own Shares24/11/05 Holding(s) in Company24/11/05 Transaction in Own Shares23/11/05 Holding(s) in Company22/11/05 Nexium22/11/05 Transaction in Own Shares21/11/05 Transaction in Own Shares18/11/05 Transaction in Own Shares17/11/05 Holding(s) in Company17/11/05 Transaction in Own Shares16/11/05 Transaction in Own Shares15/11/05 Transaction in Own Shares14/11/05 Transaction in Own Shares11/11/05 Transaction in Own Shares10/11/05 Transaction in Own Shares09/11/05 Seroquel07/11/05 Transaction in Own Shares04/11/05 Transaction in Own Shares03/11/05 Transaction in Own Shares01/11/05 Holding(s) in Company31/10/05 Zactima31/10/05 Transaction in Own Shares28/10/05 Holding(s) in Company27/10/05 3rd Quarter Results (in 2 parts)26/10/05 Notice of Results21/10/05 Seroquel18/10/05 Nexium ANDA03/10/05 Transaction in Own Shares29/09/05 Transaction in Own Shares28/09/05 Seroquel ANDA28/09/05 Transaction in Own Shares23/09/05 Regulatory Application22/09/05 Transaction in Own Shares21/09/05 Transaction in Own Shares20/09/05 Transaction in Own Shares16/09/05 Transaction in Own Shares15/09/05 Transaction in Own Shares14/09/05 Transaction in Own Shares13/09/05 Transaction in Own Shares09/09/05 Transaction in Own Shares07/09/05 Transaction in Own Shares05/09/05 Transaction in Own Shares31/08/05 Transaction in Own Shares26/08/05 Transaction in Own Shares25/08/05 Director/PDMR Shareholding24/08/05 Transaction in Own Shares23/08/05 Transaction in Own Shares19/08/05 Transaction in Own Shares18/08/05 Transaction in Own Shares17/08/05 Transaction in Own Shares15/08/05 Transaction in Own Shares12/08/05 Transaction in Own Shares11/08/05 Transaction in Own Shares10/08/05 Transaction in Own Shares08/08/05 Transaction in Own Shares04/08/05 Transaction in Own Shares02/08/05 Holding(s) in Company28/07/05 Interim Results (in 2 parts)28/07/05 Directorate Change27/07/05 Notice of Results01/07/05 Acquisition01/07/05 Transaction in Own Shares30/06/05 Director Shareholding30/06/05 Transaction in Own Shares24/06/05 Transaction in Own Shares21/06/05 Transaction in Own Shares17/06/05 Transaction in Own Shares16/06/05 Transaction in Own Shares15/06/05 Outcome of EC Investigation10/06/05 Transaction in Own Shares08/06/05 Transaction in Own Shares07/06/05 Transaction in Own Shares06/06/05 Transaction in Own Shares02/06/05 Transaction in Own Shares01/06/05 Director Shareholding01/06/05 Transaction in Own Shares31/05/05 Transaction in Own Shares27/05/05 Transaction in Own Shares25/05/05 Transaction in Own Shares24/05/05 Transaction in Own Shares23/05/05 Director Shareholding20/05/05 Transaction in Own Shares17/05/05 Transaction in Own Shares16/05/05 Transaction in Own Shares11/05/05 Transaction in Own Shares10/05/05 Transaction in Own Shares06/05/05 Director Shareholding06/05/05 AGM Resolutions06/05/05 Transaction in Own Shares05/05/05 Director Shareholding04/05/05 Cerovive28/04/05 Result of AGM28/04/05 1st Quarter Results (in 2 parts)27/04/05 Notice of Results07/04/05 Director Shareholding01/04/05 Nexium31/03/05 Director Shareholding29/03/05 Director Shareholding29/04/05 Director Shareholding23/03/05 Notice of AGM21/03/05 Transaction in Own Shares18/03/05 Transaction in Own Shares17/03/05 Transaction in Own Shares15/03/05 Director Shareholding14/03/05 Directorate Change14/03/05 Transaction in Own Shares10/03/05 Transaction in Own Shares08/03/05 Transaction in Own Shares03/03/05 Holding(s) in Company03/03/05 Holding(s) in Company02/03/05 Transaction in Own Shares'01/03/05 Director Shareholding28/02/05 Transaction in Own Shares25/02/05 Transaction in Own Shares24/02/05 Transaction in Own Shares23/02/05 Regulatory Approval22/02/05 Annual Report and Accounts21/02/05 Transaction in Own Shares15/02/05 Transaction in Own Shares14/02/05 Transaction in Own Shares11/02/05 Transaction in Own Shares10/02/05 Transaction in Own Shares07/02/05 Transaction in Own Shares04/02/05 Transaction in Own Shares02/02/05 Transaction in Own Shares All of the above documents are available for download on the Prices and Newssection of the London Stock Exchange website, www.londonstockexchange.com. 2. Documents filed at Companies House All of the documents below were filed with the Registrar of Companies in Englandand Wales on or around the dates indicated. Date Document type 08/03/06 Form 169 - Return by a Company Purchasing its Own Shares08/03/06 Form 169 - Return by a Company Purchasing its Own Shares27/01/06 Form 169 - Return by a Company Purchasing its Own Shares11/01/06 Form 88(2)R - Return of an Allotment of Shares11/01/06 Form 88(2)R- Return of an Allotment of Shares11/01/06 Form 88(2)R- Return of an Allotment of Shares11/01/06 Form 88(2)R- Return of an Allotment of Shares11/01/06 Form 88(2)R- Return of an Allotment of Shares04/01/06 Form 288b - Director Resigned06/01/06 Form 169 - Return by a Company Purchasing its Own Shares06/01/06 Form 169 - Return by a Company Purchasing its Own Shares21/12/05 Form 169 - Return by a Company Purchasing its Own Shares21/12/05 Form 169 - Return by a Company Purchasing its Own Shares21/12/06 Form 169 - Return by a Company Purchasing its Own Shares13/12/06 Form 169 - Return by a Company Purchasing its Own Shares13/12/06 Form 169 - Return by a Company Purchasing its Own Shares13/12/06 Form 169 - Return by a Company Purchasing its Own Shares14/11/05 Interim Accounts made up to 30/09/0527/10/05 Form 169 - Return by a Company Purchasing its Own Shares27/10/05 Form 169 - Return by a Company Purchasing its Own Shares24/10/05 Form 88(2)R - Return of an Allotment of Shares24/10/05 Form 88(2)R - Return of an Allotment of Shares24/10/05 Form 88(2)R - Return of an Allotment of Shares24/10/05 Form 88(2)R - Return of an Allotment of Shares24/10/05 Form 88(2)R - Return of an Allotment of Shares24/10/05 Form 88(2)R - Return of an Allotment of Shares24/10/05 Form 88(2)R - Return of an Allotment of Shares11/10/05 Form 169 - Return by a Company Purchasing its Own Shares11/10/05 Form 169 - Return by a Company Purchasing its Own Shares11/10/05 Form 169 - Return by a Company Purchasing its Own Shares11/10/05 Form 169 - Return by a Company Purchasing its Own Shares14/09/05 Form 169 - Return by a Company Purchasing its Own Shares14/09/05 Form 169 - Return by a Company Purchasing its Own Shares14/09/05 Form 169 - Return by a Company Purchasing its Own Shares22/08/05 Interim Accounts made up to 30/06/0509/08/05 Form 88(2)R - Return of an Allotment of Shares02/08/05 Form 169 - Return by a Company Purchasing its Own Shares02/08/05 Form 169 - Return by a Company Purchasing its Own Shares02/08/05 Form 169 - Return by a Company Purchasing its Own Shares20/07/05 Form 88(2)R - Return of an Allotment of Shares20/07/05 Form 88(2)R - Return of an Allotment of Shares08/07/05 Form 169 - Return by a Company Purchasing its Own Shares08/07/05 Form 169 - Return by a Company Purchasing its Own Shares08/07/05 Form 169 - Return by a Company Purchasing its Own Shares08/07/05 Form 169 - Return by a Company Purchasing its Own Shares08/07/05 Form 169 - Return by a Company Purchasing its Own Shares30/06/05 Form 88(2)R - Return of an Allotment of Shares09/06/05 Form 363s - Return made up to 15/05/0506/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares06/06/05 Form 88(2)R - Return of an Allotment of Shares01/06/05 Group of Companies' Accounts made up to 31/12/0412/05/05 Resolution to disapply pre-emption rights, to give authority to allot shares and to ratify financial assistance for the acquisition of shares29/04/05 Form 169 - Return by a Company Purchasing its Own Shares21/04/05 Form 288a - Director Appointed31/03/05 Form 169 - Return by a Company Purchasing its Own Shares31/03/05 Form 169 - Return by a Company Purchasing its Own Shares31/03/05 Form 169 - Return by a Company Purchasing its Own Shares10/03/05 Form 288a - Director Appointed02/03/05 Form 169 - Return by a Company Purchasing its Own Shares02/03/05 Form 169 - Return by a Company Purchasing its Own Shares01/03/05 Form 169 - Return by a Company Purchasing its Own Shares01/03/05 Form 169 - Return by a Company Purchasing its Own Shares All of the documents above are available for download from the Companies Housewebsite at www.companieshouse.gov.uk, or can be obtained from Companies House,Crown Way, Maindy, Cardiff, CF14 3UZ. 3. Documents submitted to the FSA All the documents below were submitted to the FSA on or around the datesindicated. Date Document 16/03/06 Notice of AGM 2006 16/03/06 Annual Report and Form 20-F Information 2005 16/03/06 Annual Review 2005 16/03/06 Summary CR Report 2005 04/05/05 Resolutions after AGM 2005 17/03/05 Notice of AGM 2005 17/03/05 Annual Report and Form 20-F Information 2004 17/03/05 Annual Review 2004 17/03/05 Summary CR Report 2004 Documents submitted to the FSA can be viewed at the Document Viewing Facilitysituated at The Financial Services Authority, 25 The North Colonnade, CanaryWharf, London, E14 5HS. The Notices of AGM, Annual Reports and Form 20-F Information, Annual Reviews andSummary CR Reports are also available via the Investors section of our website,www.astrazeneca.com. 4. Documents lodged with the Securities and Exchange Commission The documents listed below were filed with the SEC on or around the datesindicated. Date Document 23/03/06 Annual Reports14/03/06 Quarterly Reports14/03/06 Quarterly Reports10/03/06 Quarterly Reports10/02/06 Insider Trading09/02/06 Quarterly Reports06/02/06 Quarterly Reports06/01/06 Quarterly Reports02/12/05 Quarterly Reports08/11/05 Quarterly Reports05/10/05 Quarterly Reports09/09/05 Quarterly Reports05/08/05 Quarterly Reports05/07/05 Quarterly Reports29/06/05 Annual Reports06/06/05 Quarterly Reports10/05/05 Registration Statements06/05/05 Quarterly Reports21/03/05 Annual Reports24/03/05 Quarterly Reports All of the documents above are available for viewing on the Investor section ofour website, www.astrazeneca.com. 5. Further Information Further information about AstraZeneca PLC can be found at our website,www.astrazeneca.com. This information is provided by RNS The company news service from the London Stock Exchange

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