Announcement of meeting with analysts & investors

Banco Santander, S.A. ("Banco Santander" or the "Bank"), in compliance with the Securities Market legislation, hereby communicates the following:

RELEVANT information

Banco Santander hereby advises that today, Friday 12th April 2019, a presentation will take place to analysts through a conference call at 8:30 am hours (Madrid time) regarding the Bank's intention to make an offer to acquire all shares of Banco Santander (Mexico), S.A. ("Santander Mexico") not already held by the Santander Group, representing up to approximately 25% of Santander Mexico's share capital.

The presentation to analysts can be followed via the telephone number UK Dial-In Number: +442071943759; Spain Dial-In Number: +34911140101. Direct Event passcode: 92114358#

Likewise, this presentation to analysts will be made public prior to its commencement via its notification to the CNMV and publication on the aforementioned corporate website.

Boadilla del Monte (Madrid), 12 April 2019