Amended Notice of Interest in Shares

TR-1 NOTIFICATION OF MAJOR INTEREST IN SHARES

1. Identity of the issuer or the underlying issuerof existing shares to which voting rights areattached: ii

Sphere Medical Holding

Gbp0.01

2 Reason for the notification (please tick the appropriate box or boxes):

An acquisition or disposal of voting rights

P

An acquisition or disposal of financial instruments which may result in the acquisition of shares already issued to which voting rights are attached

An event changing the breakdown of voting rights

Other (please specify):

3. Full name of person(s) subject to thenotification obligation:

Royal London Asset Management

4. Full name of shareholder(s)  (if different from 3.):

-

5. Date of the transaction (and date onwhich the threshold is crossed orreached if different):

12 Dec 2011

6. Date on which issuer notified:

13 Dec 2011

7. Threshold(s) that is/are crossed orreached:

Above 3%

8. Notified details:

A: Voting rights attached to shares

Class/type ofshares

if possible usingthe ISIN CODE

Situation previousto the triggeringtransaction

Resulting situation after the triggering transaction

NumberofShares

NumberofVotingRights

Numberof shares

Number of votingrights

% of voting rights

Direct

Direct

Indirect

Direct

Indirect

GB00B551W951

1,081,081

2.9372%

1,331,081

1,331,081

n/a

3.6165%

n/a

B: Financial Instruments

Resulting situation after the triggering transaction

Type of financialinstrument

Expirationdate

Exercise/Conversion Period/ Date

Number of votingrights that may beacquired if theinstrument isexercised/ converted.

% of votingrights

N/A

Total (A+B+C)

Number of voting rights

Percentage of voting rights

1,331,081

3.6165%

9. Chain of controlled undertakings through which the voting rights and/or thefinancial instruments are effectively held, if applicable:

Proxy Voting:

10. Name of the proxy holder:

N/A

11. Number of voting rights proxy holder will ceaseto hold:

N/A

12. Date on which proxy holder will cease to holdvoting rights:

N/A

13. Additional information:

N/A

14. Contact name:

Maureen Ruddy

15. Contact telephone number:

020 7506 6634