Adviser - Change of Name

Epistem Holdings Plc ("Epistem")

Adviser - Change of Name

Epistem has been advised that, with effect from Monday 13 December 2010, its Nominated Adviser and Broker changed its name from Peel Hunt Limited to Peel Hunt LLP.

For further information, please contact:

Epistem Plc

Matthew Walls Chief Executive Officer +44 (0) 161 606 7258

John Rylands Finance Director +44 (0) 161 606 7258

Peel Hunt LLP (Nominated Adviser) +44 (0) 20 7418 8900

James Steel

Vijay Barathan