15th Nov 2024 10:33
(Alliance News) - The following stocks are the leading risers and fallers on AIM on Friday.
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AIM - WINNERS
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Angle PLC, up 10% at 12 pence, 12-month range 7.25p-31.4p. The liquid biopsy company is showcasing two new testing products at the American Association for Cancer Research's 'Special Conference in Cancer Research, Liquid Biopsy: From Discovery to Clinical Implementation' this week. Angle says its CYC PD-L1 assay enables longitudinal monitoring of 'Programmed Death Ligand-1' status in lung cancer patients and may help to advance personalised treatment. Explains: "PD-L1 allows cancer cells to evade the host immune response when unregulated, and assessment of PD-L1 status in tumour tissue can indicate if immunotherapy has the potential to be an effective treatment." Says the assay identified circulating tumour cells in 91% of metastatic lung cancer patients assessed as part of an ongoing longitudinal study. Secondly, Angle is presenting results from work to develop a Parsortix-based HER2 assay kit. Company and BioView are co-developing the kit for the evaluation of HER2 gene amplification and protein expression in CTCs harvested using the Parsortix system from the blood of metastatic breast cancer patients. "[Our] study identified cases where HER2 status had changed over time and patients who were initially HER2 negative had, in the time elapsed since tissue biopsy, become HER2 positive based on their CTC analysis," Angle says.
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GreenRoc Strategic Materials PLC, up 15% at 1.55 pence, 12-month range 1.05p-3.69p. The Greenland-focused critical mineral project developer "is pleased to announce" that Greenland's government has decided GreenRoc's exploitation licence application for the Amitsoq graphite project. Says the Mineral Licence & Safety Authority has sent GreenRoc's 2023 mineral resource evaluation to an independent third party for compliance assessment. Says the next step is for the MLSA, assuming the MRE gets a positive review, to draft a recommendation to the government on whether to approve Amitsoq's terms of reference for public pre-consultation.
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AIM - LOSERS
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Solid State PLC, down 32% at 145p, 12-month range 145p-306p. Says its full-year results "will be materially below current consensus expectations", following news of an expenditure delay regarding some potential orders from customers in the defence sector. Says expenditure has been paused on a prominent defence order programme, "we believe pending completion of the UK government's strategic defence review next summer". Says it is confident the hold-up is temporary and it will still get the orders "in due course". However this will fall outside the current financial year. Adds that it remains uncertain whether orders and deliveries expected in the next financial year will also be affected. Solid State expects to release interim results in December. Chief Executive Officer Gary Marsh comments: "There is strong demand for our technology [...] While the current delays in receiving orders are frustrating, our relationships with the forces and key defence prime contractors underpins our confidence in the group's position within this sector. The board remains optimistic about the medium and long-term outlook for defence spending given the current geopolitical climate. Aside from this order deferral, the open order book continues to improve across our target markets."
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By Emma Curzon, Alliance News reporter
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