Director/PDMR Shareholding

GlaxoSmithKline plc

Notification of Transactions of Directors, Persons Discharging Managerial Responsibilities or Connected Persons

In accordance with DTR 3.1.4R(1)(a) I give below details of changes in the interests of Mr W Louv, a Person Discharging Managerial Responsibilities, in the American Depositary Shares ('ADSs')  of GlaxoSmithKline plc (the 'Company'):

The exercise of options over 11,870 GSK ADSs on 17 November 2014, granted on 2 December 2004 under the GlaxoSmithKline Share Option Plan at a price of $43.73 per ADS, and the sale of 11,870 GSK ADSs at a price of $45.93 on 17 November 2014.

The Company was advised of the transaction on 18 November 2014.

V A Whyte

Company Secretary

18 November 2014